Age Management Medicine News Letter - 070506

One of the goals of an Age Management Medicine program is obviously to feel better. Many of us are plagued by various aches and pains as we age. Often these aches and pains are related to increased levels of inflammation in the body caused by hormonal imbalances, poor diet, lack of exercise, and being over weight.

As a result many Americans rely heavily on various over the counter and prescription pain relievers on a regular basis.

Lowering levels of inflammation in your body may allow you to reduce your dependence on medications which themselves may present health risks as described in this article about acetaminophen.

One of the laboratory markers of health used in Age Management Medicine is the CRP which is a measure of inflammation in the body. This value is positively impacted though hormonal optimization, nutritional supplementation, and life style changes. To me this seems like a better option than simply masking the symptoms.

Lowering this value also reduces your risk of heart disease, stroke and Alzheimer's disease.

Tylenol found to cause liver damage even in small doses

(NewsTarget) -- Healthy adults who took the maximum dose of Tylenol for two weeks were found to have liver damage, according to a study appearing in the latest issue of the Journal of the American Medical Association. Researchers instructed 106 study participants to take 4 grams of Tylenol (eight extra-strength tablets) a day for two weeks, with some taking only Tylenol, and some taking Tylenol combined with an opioid painkiller. The rest of the participants were given a placebo.

Nearly 40 percent of the participants taking Tylenol or the Tylenol/opioid combination displayed abnormal liver test results that indicated liver damage, while those taking the placebo showed no damage.

The study's co-author, Dr. Neil Kaplowitz of the University of Southern California said, "I would urge the public not to exceed 4 grams a day. This is a drug that has a rather narrow safety window." Kaplowitz added that heavy drinkers should not exceed 2 grams a day.

Tylenol maker McNeil Consumer & Specialty Pharmaceuticals said it had conducted its own research that tracked high-dose Tylenol users over longer periods than the Kaplowitz study, and found that its product did not lead to liver disease.

Kaplowitz and co-author Dr. Paul Watkins of the University of North Carolina were hired by Purdue Pharma, which makes the prescription painkiller OxyContin, to see why people testing a drug containing acetaminophen and the opiate hydrocodone were having abnormal liver tests. Contrary to the researchers' theories, they found that acetaminophen was the culprit.

Acetaminophen is Americans' over-the-counter painkiller of choice. Acetaminophen overdose is also the leading cause of acute liver failure.

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